Science Inside

Researchers have studied the effect of Tesnor® in multiple human studies and in an animal study

Clinical Study One

Tesnor® improves testosterone level in Healthy Young Males (21-35yr) in a Randomized, Double-Blind, Placebo-Controlled Study.

The primary outcome showed that Tesnor® had improved the serum testosterone level (free and total) of the active group compared with the placebo.

Secondary outcomes of increased hormones (dihydrotestosterone, estradiol, LH, cortisol in serum), handgrip strength and mid-upper arm circumference.

Tesnor® significantly increases free-Testosterone level in healthy young males.

Free Testosterone (in Serum)

Each bar presents Mean ± SD of Free Testosterone (pg/ml) in serum. * and # indicate significance (p<0.05) in intragroup comparison vs. baseline (paired t-test) and intergroup comparison vs. placebo (ANCOVA), respectively.

Total Testosterone (in Serum)

Each bar presents Mean ± SD of Total Testosterone (ng/ml) in serum. * and # indicate significance (p<0.05) in intragroup comparison vs.  baseline (paired t-test) and intergroup comparison vs. placebo (ANCOVA), respectively.

Handgrip Strength

Tesnor® significantly improves handgrip strength in healthy young males
Each bar represent mean % change of Handgrip strength from baseline. * and # indicate significance (p<0.05) in intragroup comparison, vs. baseline (paired t-test) and intergroup comparison vs. placebo (ANCOVA), respectively.
Tesnor® significantly improves handgrip strength in healthy young males
Each bar represent mean % change of the left- and right Mid Upper-arm Circumferences from baseline. * and # indicate significance (p<0.05) in intragroup comparison, vs. baseline (paired t-test) and intergroup comparison vs.  placebo (ANCOVA), respectively.

Sreeramaneni PGA, Yalamanchi A, Konda MR, Cherukuri SHV, Maroon JC. A Proprietary Herbal Blend Containing Extracts of Punica granatum Fruit Rind and Theobroma cocoa Seeds Increases Serum Testosterone Level in Healthy Young Males: A Randomized, Double-Blind Placebo-Controlled Study. J Diet Suppl. 2022 Feb 6:1-17. doi: 10.1080/19390211.2022.2035037. Epub ahead of print. PMID: 35129040.

Clinical Study Two

Tesnor® reduces Aging Male Symptoms scores and improves testosterone level in aging males (36-55yr) in a Randomized, Double Blind, Placebo-Controlled Study.

A second clinical study with 131 males aged 36-55, showed a reduction of Aging Male Symptoms (AMS) scores and improved testosterone levels when compared to the placebo. Also improved the serum testosterone level (fee and total) of the active group compared with the placebo.
The bars represent Mean ± SD of AMS score, * indicate significance (p<0.05) intergroup comparison vs. placebo (ANCOVA).
⦁ Tesnor® significantly improves PSS-10 scores and reduces stress in subjects
⦁ Tesnor® significantly improves Handgrip strength
⦁ Tesnor® significantly improves Free Testosterone levels
⦁ Tesnor® significantly improves Total Testosterone levels
*Internal summary report of clinical trial currently under peer review

Animal Study

Serum Testosterone level in Sprague Dawley rats A synergistic blend of two herbal extracts increases cellular Testosterone production and inhibits Aromatase activity in vitro.  Increases serum Testosterone level by 45% in 14 days and improves semen quality compared with control Sprague Dawley rats.
⦁ Tesnor® improves serum Testosterone level
⦁ Tesnor® improves semen parameters in Sprague Dawley rats
⦁ Tesnor® improves semen quality in Sprague Dawley rats

Regulatory

Tesnor® is a well-researched ingredient with an excellent safety profile which meets global regulations.
⦁ Tesnor® is tested with NSF and LGC for absence of WADA prohibited substances.
Suitable for multiple applications including beverages; shots; powders.